癌症科学与治疗

口服长春瑞滨治疗 HER-2 阴性转移性乳腺癌的 II 期临床研究

Abstract

Rasha Abd El-Ghany Khedr* ? Amr Abd El-Aziz Ghannam

???????????????? (MBC) ???????????????????? II ???????????????????????? (MBC) ?????????????

?????? 21 ??? > 18 ??????????? HER-2 ?? MBC ???????????????????????60 mg/m2?3 ????? 1 ??? 8 ?????? 1 ??? 8 ???? 80 mg/m2?????????????????????????????????????????????

??? 28.7% ??? (6/21) ????????????? 66.8% (14/21)?? 1 ??? (4.8%) ??????????????????? (PFS) ????? (OS) ??? 6 ??? 16 ???1 ? OS ? PFS ???? 64.1% ? 16.2%??????????????????? 3/4 ??????????????? (9.5%)?????? 3/4 ??????????/?? (14.3%)?????????????????

??????????? MBC ?????????????????????????????????????????????????????????????