临床病例报告杂志

Acute Dystonic Reaction Associated with Cefuroxime Axetil in a Child Running Title: Acute Dystonic Reaction

Abstract

Gokhan Ersunan, Ozlem Bilir, Asim Kalkan, Ozcan Yavasi and Kamil Kayayurt

Dystonia is an extra-pyramidal motor function disorder characterized by intermittent spasmodic or sustained involuntary muscle contractions of the face, neck, trunk, pelvis and extremities causing repetitive movements and postural abnormalities. A 10-year-old male child was presented to the emergency department with complaint of regular rhythmic spasms on the head. He was diagnosed as dystonic reaction induced by cefuroxime axetil. After cessation of the therapy and administration of 2.5 mg of biperiden intravenously, the spasms were stopped. Our aim is to make up an awareness of this adverse drug reaction when prescribing such antibiotic in children.