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Advancing Nanomaterials for Detection of Organophosphorus Nerve Agents in Forensic Application: A Review

Abstract

Amar Pal Singh, R.K Sarin, Utkarsh Jain Nidhi Chauhan

The pesticide poisoning cases are one of the most common referred for examination in Forensic Laboratories. Currently, these laboratories detect pesticides in visceral samples by using conventional techniques namely Thin-layer Chromatography, Gas Chromatography, High-Performance Liquid Chromatography and Gas Chromatography–Mass Spectrometry techniques in antemortem and postmortem crime exhibits. However, these techniques are constrained by various factors including low sensitivity, efficiency, time consumption, high cost and require trained personnel to operate. The rapid development in the field of nanotechnology and nanomaterials will certainly pave the way for the development of new methods for detection of Organophosphorus pesticides in exhibits referred for forensic examination with the potentials to overcome the limitations of the conventional techniques. The researchers of various disciplines including chemical, biological, physical, medicine, explosive, fingerprinting, environment and biochemistry are exploring the Nanomaterials and Nanotechniques. Various Nanomaterials based sensors and detection techniques have been developed which have been found powerful tools for pesticides detection at very low level in food samples and contaminated water. These Nanotechniques and Nanomaterials may render great help in detection of pesticides in poisoning cases. Therefore, in forensic examination, it is decisive to apply the novel promising Nanomaterials and Nanotechniques for detection of OrganoPhosphorus (OP) pesticides with high sensitivity, selectively and rapidity.

This review paper provides an insight of using nanomaterials based techniques for detection of OP pesticides

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