血液与淋巴杂志

蘇丹人糖尿病視網膜病變中 0f Gpx-198C/T 基因多態性 (rs1050450-198C/T) 的關聯

Abstract

Albadawi NMN*?Tarazawi EA?Ismail AM?Altoum S ? Bakheet KH

?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????GPX-198C/T?rs1050450??????????????????????????GPX???????????? FBS?HbA1c ?????????????????????????????? 130 ?????n 60????????????????n 70???????????????????? 22 ? 80 ???? Makkah Eye Complex???DNA?PCR??GPX?Aba1?????????????????Cobas Int 400???????????????????GPX?????FBS?TG?CHOL?HbA1c???????????????????????????2?=1.9:1?????????II ?? 1 ?????? DR ???DNR ? GPX ?????? (p=0.003)? DR ??? HbA1c ? FBG ???????? DNR p=0.001 ? p=0.001????? DR ? DNR ??????? CHOL ? TG ???????????? GPX-198C/T ??????????? 33 ??47%???? CC ?????? 13?22%???? CC ???GPX-198C/T SNP rs1050450??????????????OR=0.310?95% CI=0.176-0.486?p=0.001?????25?42%????????TT ?????????????14?20%??????SNP?TT ????GPX-198C/T SNP rs1050450?????????????OR=2.4?95% CI=1.10-5.90?p=0.004??????C???????????????48%??????T?????????????????72%?OR=0.357?0.216-0.433?? p=0.001????????GPX-198C/T?rs1050450??????????????????????????????????? T ??? GPX ????????????