癌症科学与治疗

急性淋巴细胞白血病儿童中的 CD44 和 CD44 变体 6

Abstract

Ahmad A Omran?Esmat A Elsharkawy?Ayman G Ghobrial?Hosny B Hamed?Waleed M Abd el Hameed?Nagwa I Okaily ? Abdel-Azeem M. El-Marazy

??????????????? (ALL) ??????????????????????????????????? CD44 ?????????????????????CD44v6 ? CD44 ????????????????????????????????????????????????????????? CD44 ? CD44v6 ???????? ALL ?????????????????

??????????? 57 ???????? 1 ??? 40 ?????????????????????????? 2 ??? 17 ???????????????????????????????????????????????????????????????CBC?Leishman ?????????LDH???????????????????????????????? BM/PB ?????????????????????????????????????????? RTPCR ??????? CD44 ? CD44v6 mRNA ???

??? I?CD44??????II??P=0.001???CD44v6?I?II???????????CD44%?LDH???????????????????????r=0.64?P=0.001&r=0.62?P=0.001&r=0.92?P=0.001???CD44%??????HB????????????????r=-0.93?P=0.001&r=-0.92?P=0.001????????CD44%?????????????/??????????????????? CD44v6 ??????????????????P=0.1??? ALL ??? CD44 v6?HB ???????????????LDH ??? BM ???????????

??? CD44??CD44v6???????ALL?????????????CD44????????????