肾脏病学与治疗学杂志

???????????????? 24 ????? 37.5 ??????????? 14 ??????????????????????????????7?8?9?11??????????????????????????????????????????????1?

?????????????????????????????????? 2,3,4,5,6???????????????????? (AKI) ??????????????????????????????????????????????????????????

AKI ??????????????????????????????????????????????? 10,11,12,13?????????????????????????????????????????????????????????????????????????????????????????????? 1,2?

???????? SSIMS ? RC ????????????????????????????????

??????????????? SS ???????????????????????????????????????

AKI ????????????????????????????????????????????????????? AKI ????????

???? KDIGO4,5,15,16 AKI ?? - AKI ???????????

• 48???SCr??≥0.3mg/dl(≥26.5μmol/l)??
• SCr ???≥1.5 ????????????? 7 ??????
• 6?????<0.5 ml/kg/h?

?????????????????

?????

The cases which meet the incorporation and avoidance measures will be read for year and a half.

Study Duration: year and a half.

Incorporation Criteria: -

Patients over 18 years old having intense febrile disease with platelet check under 1.5 lakhs/cumm with intense kidney injury because of Dengue, Malaria, Leptospira contamination, Ricketssial fever, Typhoid and Chikungunya will be taken after research center affirmation.

Rejection Criteria: -

• Patients under 18 years.
• Pregnant ladies.
• Snake nibble.

Bacterial sepsis – Clinical and Radiological highlights reminiscent of pyelonephritis, pneumonia, meningitis, gastroenteritis, intense viral hepatitis and intra stomach sore. Immunocompromised, Acquired thrombocytopenia, persistent liver sickness.

Techniques:

Proposed technique for measurable examination: -

The information is gathered from the inpatients of SS establishment of clinical science and examination focus will be broke down, the outcomes will be classified.

Procedure:

A complete number of hospitalized Patients of Acute febrile ailment with Thrombocytopenia is read for year and a half period and to associate the turn of events and range of intense kidney injury among them and its result is estimated.

On the off chance that standard creatinine isn't referred to, we have considered as 0.8. We have likewise seen the decrease of creatinine in the medical clinic stay till release for thinking about a case as intense kidney injury.

Result is estimated by eGFR utilizing MDRD equation at release of the patient and separated into three gatherings,

• Complete recuperation: >60ml per min.
• Partial recuperation: 60-15 ml for each min.
• No recuperation: <15 ml per min.
• Death.

RESULTS:

The present observational cross sectional investigation was done in the Department of general medication, SSIMS and RC, Davangere. We assessed 100 patients who were having intense kidney injury in intense febrile disease with thrombocytopenia and contemplated their result till release. Intense kidney injury is one of the significant inconveniences of intense febrile sickness with thrombocytopenia. This examination writes about seriousness and range of intense kidney injury among the different intense febrile sickness with thrombocytopenia for the range of year and a half from 2016 to 2018, its administration and result till release.

????????????? 100 ??????????????????????????????? 18 ?????????????? 65 ???????? 36.5 +/- 9.7 ??????????????????????? 100 ?????38 ??38%???????62 ??62%???????2018 ???? HCV ???? 5.87/100,000?? 2016 ??????????? 1.4 ??????HCV ??????????Liu et al.?2018??????????????? HCV ?????????????????????? (HCC) ??????????? (Polaris Observatory, 2017)?HCV ?????????????????????

??????? (DAA) ????????????????? (SVR) ?? (?????????2018)?????? HCV ???????? DAA????????????????? (Feld ???2015?Forns ???2017)???? (GT) 3 (Kwo ???2017) ???????? (Feld ???2015?Lawitz ???2017) ????????? HCV ???????? DAA ??????????????????????????????????????? DAA ?????? (Bian ???2017)?????? HCV ?????????????????????? 2018 ? 4 ??????????????? HCV ?? (Bureau, 2018)??????????? DAA ?????? (SOF)?????/???? (EBR/GZR)???????????????????? (OBV/PTV/r/DSV)????? (DCV) ????? (ASV)???????????????/???? (SOF/VEL) ?????????????????????? HCV ?????? 5,660 ??????? 85-90% (Bureau, 2018)??????????????? DAA ??????????????? HCV ???????????? DAA ??????