??·??????·?????·??????·???????·???????·???????·??????·???????·?????????·???·????????·????????·???·??-??
?????????? (DTC) ??????????????????????????ATP ??? (ABC) ???? ABCB5 ??????????????? (CRC) ???????????????????????????????? DTC ???????????????
????????? 49 ??? CRC ???????????????UICC I-IV ?????????????????????????????????? 5 ??????????????? ABCB5 ????? CD133????????????????Lgr5???????????????? (CK) 20???????????????????
??????????????????????????????????????ABCB5 ? Lgr5 ???????CD133 ? CK20 ???????????? ABCB5 ? Lgr5 ??????????????????
?????? ABCB5 ? Lgr5 ??????????????????????????????????? DTC ?????ABCB5 ? Lgr5 ???????????????????????? ABCB5 ? Lgr5 ???????????????????
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