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Comparing Tolvaptan and Loop Diuretic Treatment Outcomes in Heart Failure

Abstract

Cheol Park

Heart failure remains a significant global health burden, necessitating effective congestion management to improve patient outcomes. This retrospective study aimed to compare the long-term effects of tolvaptan and loop diuretics in the control of congestion in HF patients. Medical claims data from a diverse group of HF patients treated with either tolvaptan or loop diuretics were analyzed over several years to assess their impact on two primary outcomes: time to HF rehospitalization and time to in-hospital death. The study cohort consisted of HF patients with documented congestion symptoms and diverse comorbidities, spanning different demographic profiles. The analysis included a comprehensive examination of medical claims data, enabling the assessment of long-term treatment effects.