????·??????????·????????·??-???
??????????????????????? (CLL) ??????????? B ???????????? p-53 ?????
????? ELISA ?????? 20 ???? CLL ???? p-53 ?????????
???? II-III/IV ?????????
????? B ? CLL ???? p-53 ?????????? 15%?20
????? 17 ?? p-53 ??????? 16.76 μg/dl?CV=0.5%????? p=0.034???
?????p-53 ?????????????????1-2 ?? 15% ± 2??
3-4 ?? 100%?
???ELISA????????????CLL??????????????p-53???????
???????????
??????????CLL???????????????
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