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Effects of Cardiovascular Disease Treatment on the Remodelling and Diastolic Characteristics of the Left Ventricle

Abstract

Thomas Denney

Medications and underlying cardiovascular disease/cardiovascular disease risk factors (CVDRFs) both have an impact on left ventricular (LV) remodeling and diastolic properties. However, patients with multiple CVDRFs may not notice these effects. In a patient group with normal LV dimensions and systolic function, we looked at how different medication classes affected hemodynamics. Coronary angiography, LV pressure measurement, and cardiac magnetic resonance imaging were carried out on 38 participants (61 to 7 years old, 64 to 9 percent LV ejection fractions). The "adequacy" of medication therapy to address each existing condition with specific indication-based medication classes was taken into consideration when analyzing the effects of coronary artery disease (CAD), CVDRFs, and their corresponding medication therapy on LV parameters. According to our findings, the intensity of CAD/CVDRF treatment is correlated with the degree of LV remodeling and diastolic impairment. Exhaustive treatment of all distinguished computer aided design/CVDRFs might be a significant element for the conservation of diastolic capability.

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