Ayalew Nesgash*, Belay Yaregal, Tesfamariam Kindu and Endalkachew Hailu
Clinical anesthetic trial was conducted on twelve apparently healthy bitches presented to Gondar University Veterinary Clinic for ovariohysterectomy procedures. The aim of the study is to evaluate the effects of intravenous diazepam on physiological, hematological, and anesthetic parameters and also to assess anesthetic complications and develop anesthetic protocol for dogs. The bitches were randomly assigned into Group I and Group II. Anesthetic protocol was achieved by administration of atropine (0.04 mg/kg BW, S.C) immediately followed with xylazineketamine (1 mg/kg BW+10 mg/kg BW, I.M) for both groups but diazepam (0.5 mg/kg BW, I.V) was also given to Group I bitches when the bitches were attaining lateral recumbency. Physio-hematological and anesthetic parameters were recorded and analyzed. Quality of induction and recovery was statistically significant (P<0.05) difference between the groups. The mean of induction time was significantly (P<0.05) shorter in Group I. The mean time for loss of pedal reflex was found significantly (P<0.05) decreased in group I. Response to surgical incision and muscle relaxation was statistically significant (P<0.05) difference between groups. Duration of anesthesia, time of sternal recumbency, time of unassisted standing and duration of recovery were significantly (P<0.05) longer in Group I as compared Group II. Post anesthetic salivation was significantly (P<0.05) exhibited by Group I. No bitches were died during anesthesia or after recovery. In conclusion, atropine-Xylazine-ketamine-diazepam anesthesia does not affect physio-hematological parameter and is a very satisfactory anesthetic protocol for excellent induction, adequate muscle relaxation, longer duration of anesthesia and smooth recovery compared to atropine-Xylazineketamine anesthesia.
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