癌症科学与治疗

通过 MTT 生物测定法检测抗癌药物的功能相似性

Abstract

Takaki Hiwasa?Takanobu Utsumi?Mari Yasuraoka?Nana Hanamura?Hideaki Shimada?Hiroshi Nakajima?Motoo Kitakawa?Yasuo Iwadate?Ken-ichiro Goto?Atsushi Takeda?Kenzo Ohtsuka?Hiroyoshi Ariga ? Masaki Takiguchi

???????? Ha-ras ??? NIH3T3 ?????????????????????????? MTT ????????? 16 ??????????????????????????????????????????????????? (DCI) ????????? C/EBP??C/EBP??p53?p21?PTEN???? MDM2???????HSP90?COUP-TF1 ??????????????? DCI ????????????? ras?src?erbB2 ????????????????? DCI ???????????????????????????????????????????????????????? DCI ???????????????????? C ???????????? (r) ?????????????????????????????????????? r ??????????????????????????????????????????