癌症科学与治疗

人类乳腺癌干细胞具有比分化型乳腺癌细胞明显更高的网格蛋白非依赖性和 Caveolin 非依赖性内吞率

Abstract

Kanagaraj Palaniyandi?Barbara A Pockaj?Sandra J Gendler ? Xiu-Bao Chang

?????? (BCS) ?????????? (MDR)???????????????????????????????????????????????????? MDR ????? BCS ??????? MDR BCS ????????? MDR BCS ?????????1) ????????????????? BCS ???2) ATP ??? (ABC) ????? G ? 2 (ABCG2) ??????? 3) BCS ????????????ABCG2??????????ABCG2??????BHK?????????????????BCS????????????BCS???????????ABCG2?BHK???????????ABCG2???????????5D3??????BCS??????BCS??????????BCS?????????????MCF-7??????????????????BCS????????????????????????????????????????BCS???????????????????????????????????????????????????????????????????-β-???????????????????????????????????????????????????? BCS ??????? BCS ??????????????????????????????? BCS ????????????????????????????????? MDR BCS ??????????