免疫化学与免疫病理学

Treg 淋巴细胞在慢性丙型肝炎患者中的免疫调节作用

Abstract

Aref MI?Ibrahim IA?Ahmed SS ? El-Azim Mansour MA

?????? T ?? (Treg) ???????????????????????????????????? HCV ????Treg ?????????? HCV ???

?????????? CD4+ CD25+ Foxp3+ Tregs ??????? (CHC) ???????????

???????????????50 ????? Child-Pugh ???Child A?B ? C???? HCV ??????????25 ???????????????????????????????????????? CBC?AST?ALT?ALP?GGT?PT?INR??????????ANA????????????? HCV-Abs ????? HCV-RNA PCR ???????????????????????????? CD4 ⁺ CD25 ⁺ FoxP3+ ??? Treg ??????????

??? CHC??CD4 ⁺ 25 ⁺ FOXP3 ⁺ Treg?????????????????????CHC????Child-Pugh???3????? CD4 ⁺ 25 ⁺ FOXP3 ^{+ Treg??????????????????CD4 +} 25 ⁺ FOXP3 ⁺ Treg?????????????????

??? CHC ??? CD4 ⁺ 25 ⁺ FOXP3 ⁺ Treg ???????????? Child-Pugh ??? 3 ??????????? CD4 ⁺ 25 ⁺ FOXP3 ⁺ Treg ??? HCV ????????????????????????