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Impact of Change in Maximum Aerobic Capacity in Patients with Coronary Artery Disease: 36 Months Follow up

Abstract

Rohit S, Rahul M, Dawkhar S, Amin G and Ghadigaokar P

Objective: There is a scarcity of literature that documents the results of evidence-based traditional/complementary medicine. Aim of this study was to analyze survival benefit in patients that were treated with ayurvedic therapy called Sampurna Hridaya Shuddhikaran (SHS). Secondary endpoints were to observe a change in demographics and VO2peak.

Methods: This retrospective study analyzed data of CAD patients who received and completed 12-week SHS. Patients whose data was available before and after intervention were enrolled in the study. These patients were then approached via a telephonic call at 36 months to know their survival status and other demographic and clinical parameters.

Results: CAD patients (N=154, males: 127(82)) with a mean age of 63.19 ± 9.91 and LVEF: 50.79 ± 12.57 were enrolled in the study. Peak oxygen uptake (VO2peak) which is an independent predictor of survival benefit was documented to be increased post 12-weeks SHS treatment. At 36 months the all-cause mortality was reported to be 13%. Increase in age, gender (male/female), previous MI history was found to be associated with the mortality rate.

Conclusion: Enhanced survival percentage was observed at 36 months as compared to the documented clinical trials. Therefore, Ayurvedic interventions need to be a strong candidate for better management of CAD and survival benefits.

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