..

Induction or Exacerbation of Psoriatic Lesions During Anti-TNF- α Therapy

Abstract

Eiichi Morii

Paradoxical cases of psoriatic lesions induced or exacerbated by anti-tumor necrosis factor (TNF)-α therapy have been reported more frequently in recent years, but data related to inflammatory bowel disease (IBD) are rare. A systematic literature review was performed to provide information about this adverse effect in patients with IBD who receive anti-TNF therapy. Paradoxical cases of psoriatic lesions induced or exacerbated by anti-tumor necrosis factor (TNF)-α therapy have been reported more frequently in recent years, but data related to inflammatory bowel disease (IBD) are rare. A systematic literature review was performed to provide information about this adverse effect in patients with IBD who receive anti- TNF therapy. In the last few years, tumor necrosis factor-alpha (TNF-α) antagonists such as infliximab and adalimumab have revolutionized the treatment of inflammatory bowel disease (IBD) and psoriasis.2However, as the use of these biologic agents has increased, reactivation of latent infections, cutaneous reactions (eczematous, neoplastic, granulomatous, and psoriatic lesions), and other side effects have been documented.

免责声明: 此摘要通过人工智能工具翻译,尚未经过审核或验证

分享此文章

索引于

相关链接

arrow_upward arrow_upward