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分子生物标志物与诊断杂志

Integrin Inhibitor Drugs: New Therapy Against Metastasis

Abstract

Robert Skopec

The spread of cancer around the body-metastasis is one of the biggest challenges in cancer treatment. It is often not the primary tumor that kills, but the secondary growths. Cancer cells are able to break away from the primary site, travel around the body and seed new tumors. A key question in cancer research was how cancer cells are able to survive when they break away from a tumor to spread around the body. Cells are more protected when they are attached to other cancer cells and their surroundings. But they become more vulnerable if they detach and float and also normally undergo cell death. Metastasis is now seen as incurable and remains one of the key targets of cancer research. The question is how two molecules communicate and work together to help cancer cells survive during metastasis. We are presenting now in this article below one special drug case able to block the spread of cancer metastasis within the human body.

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