分子生物标志物与诊断杂志

Langerhans Cell Sarcoma - Review of Literature and a Rare Case Report

Abstract

Lakshmaiah KC, Smitha CS, LokanathaD, Linu AJ, Premalata CS, Usha A and Aparna S

Langerhans Cell Sarcoma (LCS) is extremely rare, with only 37 cases reported in English literature. We present the case of a 38 year old woman with a 2 month history of left neck swelling and pain. A diagnosis of LCS was made based on pathological findings of the biopsy of the tonsil. IHC on the neoplastic cells was positive for LCA, S100, CD 68 and CD1a (with membranous and paranuclear dot like patterns). A literature review is also presented to enhance the understanding of LCS and the importance of early diagnosis and treatment of this unusual lesion.