癌症科学与治疗

miR-203 通过抑制卵巢癌的上皮间质转化发挥肿瘤抑制因子的作用

Abstract

????????????????????Andrew Dudas????????????Erzsebet Szabo?Sue-Chin Lee?Michelle Sims?????Todd Tillmanns?Lawrence M. Pfeffer?Gabor Tigyi????

????????????????????????????????????miRNA ??????????? RNA????????????????????????????????????????????????? miR-203 ?????????

???????????miR-203??????SKOV3?OVCAR3????????MTT?transwell?Matrigel???????????????????????????????????

?????????????????????? miR-203 ?????????? Snai2 (slug) ????????? miR-203 ?????????????????miR-203 ?????? SKOV3 ? OVCAR3 ????????????????????miR-203 ?????????????????? (EMT)???????? (sh) RNA ?? Snai2 ??? miR-203 ??? EMT ???????????????????? miR-203 ????????????????????

??? miR-203?????????Snai2?????????