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巴基斯坦主要研究所慢性骨髓性白血病和急性淋巴性白血病 BCR-ABL 重排變異體的分子流行病學

Abstract

Hussain Ahmed Raza1?Muhammad Shariq Shaikh2?Mu??hmmad Hasan Hayat2?Hamayail Ansari1?Huzaifa Bin Rashid1?Tariq Moatter3 ? Zeeshan Ansar Ahmed3

?????????????? (CML) ????????? (ALL) ?????????????? CML ? ALL ? BCR-ABL ????????????? BCR-ABL ?????????????????????????????685 ??????644 ?CML ???41 ?ALL ??????2016 ?10 ??2019 ?7 ?? %?????? ALL ???? 35 ?????? BCR-ABL1 ?????? 65.7% ????????BCR-ABL ??????????b3a2 (63.3%) ?b2a2 (34.8%) ?????CML ???????????e1a2 (77.1%) ?b3a2 (11.3%) ?????CML?????????????????????? CML ? ALL ?????????????????????????????????? CML ???? b3a2 ????????????????????

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