神经系统疾病

Neuro-Behcet's-Disease with Severe Brainstem Affection: A Case Report of a Successful Intensive Medical Care Management

Abstract

Oikonomou P and Bäzner H

Neuro-Behcet’s-disease (NBD) refers to any neurological involvement of Behcet’s-disease (BD), which is a multisystemic vasculitis, presumably of autoimmune etiology. Few cases of neuropsychiatric manifestation of BD with severe parenchymal lesions have been reported. Clinicians who are unaware of this fact can neglect a fatal complication of BD. With respect to this diagnostic and therapeutic challenge we report of a 38-year-old man with a history of BD, who presented to our emergency department with hyperactive delirium, dysarthria, deterioration of vision, headache and nausea due to pronounced brainstem affection. After symptomatic and causal treatment in our neurological intensive care unit the patient improved clinically, reflected in the decline of pathological findings in the neuroimaging.