Kazuo Maeda*
Aims: Invasive techniques in fetal diagnosis and therapy are gradually changing to noninvasive methods, which would be presented in this article as well. Methods: Noninvasive methods in fetal diagnosis are reviewed. Results: External ultrasonic Doppler autocorrelation fetal monitor; ultrasonic Doppler fetal actocardiogram; ultrasonic 2D, 3D, 4D imaging methods, pulsed Doppler blood flow record, color and power Doppler flow mappings, gray level histogram width method in the prediction of neonatal RDS in preterm fetal lung; other tissue characterization techniques and recent noninvasive prenatal test (NIPT) in fetal diagnoses, high intensity focused ultrasound ablation for the TRAP sequence in monochorionic twins in fetal therapy were presented. Conclusion: Noninvasive methods were introduced to fetal studies to perform fetal diagnosis and therapy safely
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