肾脏病学与治疗学杂志

Omeprazole Induced Acute Interstitial Nephritis in an Adolescent

Abstract

Damien Noone *,Chia Wei Teoh ,Anthony M Dorman ,Atif Awan

Proton pump inhibitors (PPIs) have emerged as a common cause of drug induced acute interstitial nephritis (AIN) in adults. We present a 15-year-old girl with severe acute kidney injury and biopsy proven AIN attributable to omeprazole. Withdrawal of the drug and steroid therapy affected a recovery of renal function. As the use of PPIs increases in paediatrics, it is important to be aware of this rare but serious side effect.