生物医学与药物科学杂志

Pharmacokinetics and Pharmacodynamics: Bridging the Gap between Biomedical Sciences and Clinical Practice

Abstract

Andrea Flemming

Pharmacokinetics and pharmacodynamics are two fundamental concepts in the field of pharmacology that play a crucial role in understanding how drugs interact with the body and produce therapeutic effects. Pharmacokinetics focuses on the absorption, distribution, metabolism, and elimination of drugs, while pharmacodynamics examines the relationship between drug concentration and its effect on the body. This article explores the significance of pharmacokinetics and pharmacodynamics in bridging the gap between biomedical sciences and clinical practice, emphasizing their importance in optimizing drug therapy, individualizing treatment, and improving patient outcomes. Pharmacokinetics encompasses the processes by which drugs are absorbed, distributed, metabolized, and eliminated from the body. This section delves into each aspect of pharmacokinetics, highlighting their significance in drug therapy. It discusses the mechanisms of drug absorption, including factors influencing bioavailability and the role of different routes of administration.