组织科学与工程学报

Platelet Rich Plasma as a Mono Therapy for Diabetic Ulcer

Abstract

Sandeep Shrivastava, Chandrashekhar Mahakalkar, Pradeep Singh, Anirudha Chandak and S Tayde

Diabetic non-healing Ulcers are very difficult to treat. Many of such Patients undergo Amputations to lessen the morbidity. There is no defined management for them. Current management requires multiple surgical interventions, drugs and intense local dressing and care. The authors have developed an innovative therapy called as STARS (Sandeep’s technique for assisted regeneration of skin) for wound management. It is basically based on principle of regenerative medicine with autologous platelet rich Plasma (PRP) being the source of regenerative growth factors leading to complete healing of wounds. This case is a young female, a Juvenile Diabetic with non-healing infected ulcers on both heels since 3 years. She received STARS therapy and her one ulcer healed completely and second ulcer healed 40%. A complete healing of non healing diabetic ulcer without surgery, drugs and intense dressing, in an uncontrolled diabetic patient, is a milestone in such wound management. STARS therapy led by Platelet regeneration, is an innovative protocol for such cases.