癌症科学与治疗

5-氟尿嘧啶微海绵的制备及对结肠癌治疗效果评价

Abstract

Mahmoud H Othman?Gamal M Zayed?Gamal H El-Sokkary?Usama F Ali ? Ahmed AH Abdellatif

5-???? (5-FU) ????????????????????? 5-FU ???????????????????????????????????????? Eudragit RS100 ? 5-FU ??? (MS) ????????????????????? 5-FU ?? Eudragit RS100 MS?MS ??????????????????????????????????????????? MS ????????????? (SEM) ????????????????? HCT 116 ? CACO2 ????? MTT ???????????????????? MS ????????????????62.76%±1.06%?93.80%±1.75%???????71.80%±1.62%?101.3%±2.60%??????53.11μm±41.03nm?118.12μm±48.21nm?????????????5-FU?Eudragit RS100????????????????????MS???5-FU?5-FU??????????????5-FU?Eudragit RS100???????????????????5-FU????????