药物化学

Role of Aryl Urea Containing Compounds in Medicinal Chemistry

Abstract

Pratiksha Sikka, Jagdish K Sahu, Arun K Mishra and SR Hashim

Aryl urea is an entity which is being synthesized in many of its derivative form from past few years; the entity is major source of interest for many of medicinal chemist to explore its various biological activities. In present study, we review the chemistry of aryl urea and its pharmacological actions as an anticonvulsant, antimicrobial, antiviral andanti inflammatory agent by studying its various synthesized derivatives. This review can be helpful to develop various more new compounds possessing aryl urea moiety that could be better in terms of efficacy and lesser toxicity.