血液与淋巴杂志

BIRC5 基因作為小兒急性淋巴性白血病預後標記物的作用

Abstract

Al-Sharkawy E?Ghobrial AG?Eldin AMK?Sabre MM?Aboul-Fotoh LE ? El-Deen HTG

???????????????ALL????????????? Survivin ???????????? (IAP)????????????? 5 (BIRC5) ?????????? caspase ?????????????????????????????????? BIRC5 ????? ALL ???????
?????????? 42 ???? ALL ?????????????????? 10 ?????????????????????????????????????????????????????CBC????????????????????LDH?????BM??????????????BM ????????????????????? ALL ?????????? PCR ? BM ??????????????
??? ALL??BIRC5??????????P=0.0004????? BALL ? pre B-ALL ???T-ALL ??????????????P=0.001?? survivin???LDH????????WBC????????r=0.47?P=0.002?r=0.31?P=0.05?r=0.62?P=0.001???????????????????LDH ? WBC ????? 94.5% survivin ???? ALL ?????????? survivin ???? ALL ?????? 25% ?????? (P=0.001)?
??? BIRC5 ??????? ALL ?????????????????????????? ALL ???