??????????????????????????????????????????
??? ESCC???????????????S-1???ESCC????????????????????????S-1???ESCC??????????????????
??? 2007????2014?????????15????????????ESCC????S-1??????????????????
??? ?????? 70 ?????63-77 ???1 ??7%?????????CR???9 ??60%??????SD??? 5 ??33%??????PD???? 13.9 ?????????????????????? 6.2 ??? 10.0 ???1 ????? 33.3%?15 ????? 3 ??20%??? CTCAE 3 ????????2 ????? 3 ????????????1 ????? 3 ???????????????
??? S-1??????????????????ESCC??????????????????
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