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Serum Calcium, Magnesium and Parathyroid Hormone in Normal Pregnant and Pre-eclamptic Women in Karachi, Pakistan

Abstract

Rubina Aziz and Tabassum Mahboob

Objective: The objective of this study was to compare serum calcium, magnesium and Parathyroid hormone in preeclamptic women and normal pregnant females.

Materials and Methods: 32 pregnant women, preeclamptic n=16 and healthy pregnant control group n=16 with same ages and period of gestation included in present study. Serum calcium, Magnesium and Parathyroid Hormone were done by standard methods. Data are presented as mean ± SEM. P value < 0.01 was considered statistically significant.

Results: Serum calcium (7.02 ± 0.99 vs. 9.34 ± 0.57) and serum magnesium (1.3 ± 0.34 vs1.88 ± 0.16) was significantly lower in preeclamptic women than normal healthy controls. PTH (Intact) concentration was not changed as compare to normal control (24.07 ± 4.98 vs. 23.86 ± 3.30).

Conclusion: Decreased levels of serum Calcium and serum Magnesium found in our study confirms there strong relation with preeclampsia. Calcium and magnesium supplement can be used in pregnant women for the prevention of preeclampsia.

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