Saranya S, Muthuselvi S and Prema Rani M
Hydroxyapatite (HAp) having chemical formula Ca10 (PO4)6(OH)2 is the main chemical component of human bone tissue (70%), to cope up with the bone response as a bio active material. In this study Ni doped HAp powder with triclinic phase was synthesized by sol-gel method, by doping Ni of different concentrations (0.02, 0.04, 0.06, and 0.08). The various properties due to different concentration of Ni in HAp were characterized by X-ray diffraction analysis (XRD), Energy dispersive x-ray spectroscopy (EDX) and Fourier transform spectroscopy (FT-IR). The thermal gravimetric analysis (TGA-DTA) was also carried out to evaluate the stability of the synthesized HAP powder. Antibacterial activity of compounds against microbial pathogens was done using well diffusion method. High antibacterial activity was observed for Ca0.98 Ni0.02 (PO4)(OH)2. The transmission electron microscopic analysis confirms the presence of the spherical shape morphology of the prepared hydroxyapatite nanoparticle with the particle size of around 20 to 100 nm.
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