癌症科学与治疗

Aurora 激酶 A 多态性与前列腺癌患者的无复发生存期无关

Abstract

Jerry J. Jaboin?Natalie L. Ausborn?Misun Hwang?Heidi Chen?Kenneth J. Niermann?Nicholas J. Giacalone?Regina Courtney?Qiuyin Cai ? Bo Lu

???????????????? A?AURKA??????????????????SNP??????????????????????????

???? 212 ???????????????????????????? AURKA ?????????????? SNP?????????????????? ABI SNP ?????????? SNP???? AURKA ??? r2 ? 0.90 ???? SNP????????????? 0.25?

????????????????????????????????????????????????? AURKA ??????????????????????????????????????????????? p<0.001?????????????????p<0.001??? SNPs rs1468055?rs8117896?rs2064863 ? rs1468056 ?????????? RFS???? p=0.7213?p=0.5140?p=0.0714?p=0.4731?? DFS???? p=0.3282?p=0.1909?p=0.4111?p=0.5014??????

????????????????? AURKA SNPs ??????????????????