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The Insulin–heart Connection: Linking Physiology to Insulin Resistance

Abstract

Yu Xiao

The relationship between insulin and heart function is a critical yet complex aspect of human physiology. The heart, a metabolically demanding organ, relies heavily on insulin for energy regulation. Insulin, a hormone produced by the pancreas, is essential for glucose uptake in tissues and plays a pivotal role in metabolic homeostasis. Insulin resistance, a condition characterized by diminished cellular response to insulin, leads to various metabolic disorders, including Type 2 Diabetes Mellitus (T2DM) and Cardiovascular Diseases (CVD). This mini review aims to bridge the physiological aspects of insulin function with the pathological consequences of insulin resistance, highlighting the intricate connection between insulin and heart health.

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