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??ERs?NSCLC?????????????????????????????Real-time PCR????28?NSCLC?????Ers????????ERÉ'?Erβ?NSCLC??????????ERÉ'?Erβ?mRNA????????T2?????T1???????????????ERÉ'?Erβ?????????????????Ers?NSCLC?????????????Ers???siRNA????????????????Erβ??ERÉ'????E2????????????Erβ??ERÉ'???siRNA??????cyclinD1?????????????G1????????????p21Waf1/Cip1?p53??????????
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