肾脏病学与治疗学杂志

Transplanting a Kidney and having Low-Risk Prostate Cancer in Men

Abstract

Mansoor Ali* and Zaheed Ahmed

Male kidney transplant recipients and matched control men without kidney transplants showed similar rates of prostate cancer diagnosis, clinical prostate cancer features, and prostate cancer-specific death. In comparison to control males, the likelihood of developing an advanced or poorly differentiated prostate cancer did not rise with time in transplant recipients. More than half of transplant recipients had been on immunosuppression for more than 9 years, and almost half had received their transplants before PSA testing was a standard part of the pre-transplantation examination. Thus, it is unlikely that immunosuppression following kidney transplantation will have a negative impact on the beginning or advancement of prostate cancer.