微生物发病机制杂志

Unlocking the Pathobiome Evolution Clock (PEC) by Devoomics

Abstract

Mehrdad Alizadeh and Mahyar Mobasser

The phylogeny and its tools generally applicate for different aims in bioscience. In recent years, phylogeny broadly utilizes in interpreting microbiome data. The microbiome occupied the body of plants, humans, and animals and play essential roles in functional patterns for organisms. The healthbiome (microbiome) can convert to pathobiome with present happens in hosts, environments, and climate changes. The best tools for showing and drawing in changes are phylogenetic analyses in various aspects. This pathobiome has expressed a position for considered organisms in which they when will disease or weak or die. Pathobiome and its effects influence total parts of the environment and hosts. Associated microbes in pathobiome probably or certainly exposure in divergent, convergent, and parallel. Pathobiome evolution clock (PEC) is a new perspective for predictions and investigation about pathobiome effects in organisms and environments. So, pathobiome is a frontier between life and death, or it is a transition stage from health-biome to death-biome. Additionally, we introduce Devo-omic as a new concept and term for the description of the microbiome from born to death (or microbiome changes from birth to death). PEC can be accurately evaluated under devo-omics investigations.