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??????????2014?1??2016?12????65????????????????????????????????????????????????????????I???????28??????????????II???????37????????????????????
????1?????ORR?90.77%?RR?89.29%?????RR?91.89%??2??????????ORR?86.15%?RR?89.29%?????RR?83.78%??3?????BPRS?SAPS?SANS?????????????????????????P<0.05??
????1????????????????????????????????????????????????2??????????????????????????????