Omar S. Aljitawi?Marci Allen????Majed Dasouki?Sunil Abhyankar?Sid Ganguly?Joseph P. McGuirk ? Peter VanVeldhuizen
Von Hippel-Lindau (VHL) ?????????????????????????????????????????????????????????????????????????????????????????????????????????Von Hippel-Lindau ????????(CCRC) ?56 ????????????????????????????????????????(NHL)??? VHL ????????????????????????????????????????????????? VHL ? NHL ????????????????????????? VHL ???????? VHL ? RCC ??????????????????????? NHL???????
Shalvi V. Mehta?Shilin N.Shukla ? Hemangini H. Vora
??
???FLT3 ??????? AML ?????????
???????????????
???? AML ???FLT3 ???????? FLT3 mRNA ? CD135 ???????????????????? 174 ?????????????AML????????????MDS???
??FLT3 ???????ITD???????????TKD???????mRNA ?????????????????????? FLT3 ???????? AML??FLT3 ITD?FLT3 TKD???CD135???????????19%? 7%?62%??MDS??????FLT3 ITD???CD135??????????????22%?60%???????????????FLT3???FLT3 mRNA????????? FLT3 ???? FLT3 mRNA ????????????????????? AML ???????? CD135 ????????????? (DFS) ????????????????WBC ??????????????? (DFS) ????? (OS) ?????????????????? CD135 ?????????AML ???????????? FLT3 ?????????
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