Dipesh Uprety?Jayadev Manikkam Umakanthan?Keerthi Banda?Navin Victor????·????
?????????PCL???????????????????????????????????????? B ???????? PCL??? 44 ?????????????????????????????????? 12 ??????????????????????????????????????????????????????????????????????????????? 85% ????? CD19 ? CD10 ???????? CD20??????CD3 ? CD5 ???????? B ??????????????? (TDT) ?????????? B ??????????? PCL ????????????????????????????? PCL ??????????????????????????????????????????????????????????????????????????????????????????????????????
??·C·???????????????·D·??????·?????·??????·???????·???????·???????·??????·????????·?????????·T·????
??? (ch)1 ????????????? (MM) ???????????????????????? (auto-HCT) ???????????????????????? ch1 ?????? MM ?????????? MM ? ch1 ???1q ???1p ???ch1 ???????????????? 232 ? MM ???169 ????63 ?????????????????????????????????HCT ???(n=6) ??ch1 ??(n=15) ??????????PFS (p<0.001; HR= 22.93; 95% CI: 4.94-106.48) ?OS ????????ch1 ???del 13q ???(n=7)???PFS ?OS ???4.76 ?9.43 ????ch1 ????del 13q (n=8) ??????PFS ?OS ???16.79 ?35.22 ????????????????????? 24.44 ? 57.03 ????????? ch1 ????? HCT ??????????????????????
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