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临床麻醉学杂志:开放获取

体积 5, 问题 4 (2021)

研究文章

Different doses of dexmetomedine as adjuvant to bupivacaine in ultrasound guided transversus abdominis plane block in children undergoing lower abdominal surgery

Hala Kaptan and Nagwa Mohamed Doha

Post-operative pain management in pediatric patients is essential, development of safe and effective techniques is very important. (1)

Historically, pain management in children has been poor, but in the last decades many advances have been made. (2)

The transversus abdominis plane block (TAP block) have been tried successfully in adults for post-operative pain, its role in children remains unclear. (3)

TAP block was first described by Rafi in 2001(4). It is a compartmental block, it pr0vides analgesia to parietal peritoneum, skin and muscles of anterior abdominal wall(5) .

会议论文集

Conference on Anesthesiology and Critical Care

Sanebela Olivia

ME Conferences is pleased to announce the upcoming “14th International Conference on Anesthesiology and Critical Care” scheduledduring August 12, 2021. Critical Care 2021 will be an online event focused on the core understanding and major developments in the ever-expanding field of anesthesiology by fascinating experts on a global scale.
The theme of Critical Care 202 “New Innovative Opportunities to Allow Patient Engagement” targets at proclaiming information and sharing fresh ideas among the professionals, industrialists, researchers, and students from the exploration area of anesthesia, intensive care medicine, critical emergency medicine, and pain medicine.

原创研究文章

Rapid Detection of Bacterial Isolates in Wound and Body Fluid Cultures from Abdominal Surgery

Rickey Miller Jr

Abdominal surgeries produce the highest number of Surgical Site Infections (SSI) than any other surgical procedures. Pathology specimens from these procedures (either fluid or tissue) have been analyzed for bacterial isolates in diagnostic labs using various plating and culture methods for years. While these methods have been effective, newer technology and tests based on whole genome sequencing have shortened the time for microbial identification. Six different molecular diagnostic platforms: quantitative Reverse Transcription-PCR (RT-qPCR) Laboratory-Developed Test (LDT), a COBAS SARS-CoV-2 high-throughput system, three direct RT-qPCR kits, and Reverse Transcription loop-mediated isothermal AMPlification (RT-LAMP) plus rapid antigen tests were evaluated for their diagnostic capacity to detect SARS-CoV-2 RNA by 103 SARS-CoV-2 positive patient samples were tested with these 7 methods and viral RNA being detected between 50.5% - 81.6% of samples on molecular platforms. Antigens were detected only 11.7% of samples when tested by rapid antigen test. Despite varying sensitivities on the different platforms, each platform was verified as a reliable detection tool for the virus with rapid antigen testing being a less reliable option for detecting coronavirus RNA. Increased precision and sensitivity from molecular testing platforms provide more accuracy and efficiency when looking for pathogenic bacteria causing surgical site infections in recovering patients. Early detection of bacterial isolates in surgical incisions post-surgery is imperative to the recovery of patients after a procedure. This project will investigate which molecular genomic platform is better at detecting pathogenic bacteria after abdominal surgery.

评论文章

Enantiomeric Excess of Bupivacaine (S75:R25): Laboratory Study, Clinical Application and Toxicity

Luiz Eduardo Imbelloni

Local anesthetics are drugs that produce temporary and localized blockage of nerve conduction. Depending on the place of administration and the dose used, they can lead to interruption of sensitivity, autonomous innervation and motricity, and must associate properties that, in addition to efficacy, ensure safety.

Most pharmaceutical drugs are released in racemic form. The study of the chirality of substances is an important field in the pharmaceutical industry and agrochemicals. Several review articles on chirality have been published, but none of them address the presence of an enantiomeric excess. In Brazil, an enantiomeric excess local anesthetic containing 75% of the S-enantiomer and 25% of the R-enantiomer was investigated, and later approved for use in regional anesthesia.

原创研究文章

Factors Influencing Selection of Anesthesia types among Pregnant Mothers who Underwent Cesarean Section in Jimma University Specialized Hospital

Ashebir Nigussie Yirgu and Moges Daba Bikila

Abstract

Background: Caesarean delivery is one of the most commonly performed surgical procedures all over the world. The choice of anesthesia for cesarean section is regional and general anesthesia. Some of the factors influencing the choice of anesthesia type for cesarean section are the degree of urgency, maternal and fetal condition, and willingness of the mother, the experience of the anesthetists, and availability of all anesthesia equipment. Hence, the aim of this study was to identify factors influencing types of anesthesia selection for cesarean section.

Methods: A prospective cross-sectional study design was conducted on factors influencing the choice of anesthesia type for mothers who underwent cesarean section in Jimma specialized hospital from April to June, 2018. All mothers who underwent cesarean section were included. Regular supervision and follow-up were made. Descriptive statistics were used to identify factors influencing types of anesthesia. Data was entered and analysis was done using SPSS version 25.

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