法医学研究杂志

Cervical disease is the fourth normal gynaecologic malignant growth and is considered as second driving reason for death among ladies. Different procedures are applied in therapy of cervical malignant growth including radiotherapy, chemotherapy and medical procedure. Be that as it may, cervical disease cells show forceful conduct in cutting edge stages, requiring novel methodologies in their disposal. Then again, SOX proteins are record factors equipped for directing different sub-atomic pathways and their demeanour shifts during embryogenesis, infection improvement and carcinogenesis. In the current audit, our point is to uncover job of SOX record factors in cervical disease. SOX record factors play like a blade that cuts both ways in malignant growth. For example, SOX9 has both growth silencer and cancer advancing job in cervical disease. Hence, definite job of each SOX individual in cervical malignant growth has been examined to coordinate further analyses for uncovering different capabilities. SOX proteins can manage multiplication and metastasis of cervical malignant growth cells. Moreover, reaction of cervical malignant growth cells to chemotherapy and radiotherapy is firmly controlled by SOX record factors. Different downstream focuses of SOX proteins, for example, Wnt flagging, EMT and Hedgehog have been recognized. Furthermore, upstream arbiters, for example, microRNAs, lncRNAs and circRNAs can manage SOX articulation in cervical malignant growth.

Objective: This study attempts to estimate the ancestry and sex of five unknown human crania curated by the Anthropology Department at Bloomsburg University. The fallout caused by curation and public display of human skulls in the Morton Collection, University of Pennsylvania Museum of Archaeology and Anthropology prompted the Bloomsburg University administration to direct the Anthropology Department to assess the affiliation of these crania that had no clear origins.

Method: A MicroScribe G-2X digitizer was used to collect coordinate data from osteometric landmarks, which were simultaneously recorded by an analytical software called ThreeSkull (3Skull) and subsequently imported into the FORDISC 3.1 discriminant functions computer program for processing.

Result: Cranium A12022 is that of a Japanese female with a posterior probability of 0.572; cranium A22022 is that of a Hispanic/Guatemalan male with posterior probabilities of 0.523 and 0.679; cranium A42022 is that of a Guatemalan/Hispanic male with posterior probabilities of 0.48 and 0.679; cranium A52022 is that of an American Indian male with a posterior probability of 0.845; and cranium A62022 is that of a Chinese (Atayal) male with a posterior probability of 0.911.

Conclusion: For the cranium classified as American Indian, further research will continue to uncover details of the original acquisition with the eventual goal of repatriating it to the lineal American Indian descendants for reburial.

Background: Like other phenotypic traits, stature is a key indicator for identification and is influenced by a combination of genetic and environmental factors. With the alarming rise in the frequency of road, flood, intentional mutilation and natural disasters, stature or body height is one of the most significant and useful anthropometric parameters that establish a person's physical identity. It is also regarded as one of the important and significant parameters for the establishment of personal identity in forensic medical examination or anthropological studies.

Objectives: To determine stature and gender in an adult Nigerian population by measuring the percutaneous length of the arm and forearm bones.

Methods: The University of Lagos' workers, students and volunteers made up the sample group for this study, which included 222 people (115 men and 107 women) between the ages of 18 and 65. a variety of anthropological tools, including the Stadiometer, an anthropometric tool produced by SECA alpha® in Germany. The measurement was performed using calliper, weighing balance and tape that were calibrated in centimetres.

Results and Conclusion: The intercondylar breadth had the best value for statistical significance in the sex prediction made using logistic regression. The largest link with stature was found for the ulnar measurement, whereas the smallest correlation was found for the intercondylar measurement across all parameters. Both males and females can have their arm and forearm lengths measured percutaneously, which has good reliability for estimating stature and predicting sex. The intercondylar is more strongly correlated with sexual dimorphism. Simple and numerous linear regressions demonstrated that using the foot length is the most accurate technique to predict and estimate stature.