组织科学与工程学报

Cardiac precision medicine necessitates accurate disease modeling for effective therapeutic development. Leveraging human stem cells, particularly induced pluripotent stem cells (iPSCs), offers a promising avenue for recapitulating cardiac diseases in vitro. This review explores the current advancements, challenges and future prospects of utilizing iPSC-derived cardiomyocytes for disease modeling, highlighting their potential in elucidating disease mechanisms, screening drug candidates and personalizing treatment strategies.

Cellular therapies utilizing pluripotent stem cells (PSCs) hold promising potential in addressing lung damage and promoting repair. This abstract outlines recent advancements and strategies in employing PSC-derived cells for lung regeneration. We discuss the therapeutic mechanisms, challenges and future directions of PSC-based therapies in lung repair, emphasizing their transformative role in treating respiratory disorders and advancing regenerative medicine.

This paper explores the emerging frontier of regenerative medicine in the context of lung restoration through pluripotent stem cell therapy. By harnessing the transformative potential of pluripotent stem cells, researchers aim to address the limitations of current treatments for lung diseases and injuries. Through a comprehensive review of recent advancements and ongoing research efforts, this abstract highlights the promising prospects, challenges and ethical considerations associated with employing pluripotent stem cell therapy for lung restoration..