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临床呼吸疾病与护理杂志:开放获取

Advancements in Imaging Biomarkers for Normal Pressure Hydrocephalus

Abstract

Clare Hastings

Normal Pressure Hydrocephalus (NPH) is a condition characterized by an excessive accumulation of Cerebro Spinal Fluid (CSF) in the ventricles of the brain, leading to a triad of symptoms including gait disturbance, urinary incontinence and cognitive decline. NPH affects primarily elderly individuals and it is often misdiagnosed or underdiagnosed due to the overlap of symptoms with other age-related conditions such as Parkinson's disease, Alzheimer's disease, or vascular dementia. Imaging plays a critical role in the diagnosis and management of NPH and a variety of imaging markers have been proposed to aid in the differential diagnosis and prognosis of the disease. In this article, we will review the most commonly used imaging markers for NPH, including Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and cerebrospinal fluid biomarkers.

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