Fawzia Cawo
To investigate the inhibitor and hepatoprotective activity of methanolic flower extract of poisonous plant against CCl4-induced hepatotoxicity in rats.In vitro inhibitor activity of methanolic extract of flowers of poisonous plant (MENO–F) was evaluated by varied assays, together with reducing power, supermolecule peroxidation, DPPH, ABTS, superoxide, chemical group radicals and metal chelation. The hepatoprotective and in vivo inhibitor activity of MENO-F were evaluated against CCl4–induced internal organ harm in rats. The MENO-F at dose of a hundred, two hundred and four hundred mg/kg were administered orally once daily for seven days. liquid body substance catalyst levels of serum salt salt aminopherase (AST), humour salt pyruvate aminopherase (ALT), humour alkalic enzyme (ALP) and total haematoidin were calculable beside estimation of SOD (SOD) and malondialdehyde (MDA) levels in liver tissues. any histopathological examination of the liver sections was dispensed to support the induction of hepatotoxicity and hepatoprotective effectuality.
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