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生物陶瓷的开发与应用

Preparation and Physico-Chemical Characterization Studies of Fluoride Doped Bioceramics (P2O5-CaO-CaF2- Na2O) for Bone Regeneration

Abstract

Vijayakumar Chinnaswamy Thangavel1*, Pugalandhi Pandian Sankaralingam2, Poornimadevi Sakthivel1

Fluoride doped calcium-phosphate bioceramics (P2O5-CaO-CaF2-Na2O) containing different proportions of calcium fluoride (X= 0.00, 1.25, 2.50, 3.75 and 5.00 mol %) were prepared by melt quenching technique. These bioceramics were characterized for their structural, physico-chemical, and morphological properties as per the standards set for orthopedic implants. The FTIR of these materials were recorded to assess the presence of key functionalities. The density, ultrasonic velocity, elastic constants and Poisson’s ratio measurements were made to understand the effect of concentration of fluoride doping in the bioceramics. The morphological aspects of the chosen bioceramics were studied using SEM and EDS. The crystallization, melting and thermal stability of fluoride doped bioceramics were evaluated using DSC and TG studies. From these characterizations, concentration of fluoride in the mole percentage of 5 is more ideal for further clinical
application studies in bone tissue engineering.

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