环境与分析毒理学

Wildlife Toxicology: Where We Have Been and Where We Are Going

Abstract

Ronald J Kendall

Over the last three decades, the field of wildlife toxicology involving the assessment of toxic chemicals on the reproduction, health, and well-being of wildlife species has grown dramatically as a science involving both laboratory and field research. In the early years of the development of wildlife toxicology, there was a strong emphasis on laboratory toxicity tests, including LD50 and LC50 tests, particularly on species such as bobwhite quail (Colinus virginianus) and mallard ducks (Anas platyrhynchos). Laboratory tests evolved into largescale field efforts, particularly in the late 1980s and throughout the 1990s, which was facilitated by pesticide re-registration requirements to obtain data to submit to the United States Environmental Protection Agency. Now, as wildlife toxicology continues to evolve as a science, sublethal monitoring of wildlife has become much more prominent to assess health impacts. New developments in molecular biology have also allowed insight into the genetic basis for wildlife response to toxic substances. Considering the diversity of fish and wildlife species both in the United States and globally, it continues to be a great challenge to protect this diversity of wildlife species from impacts of toxic substances. As we expand and become more sophisticated in assessing field and laboratory effects of toxic substances in wildlife, we will be able to do a much better job in the future of assessing the effects of environmental contaminants on the reproduction and health of the wide array of wildlife species and developing solutions and/or mitigation strategies.