Guo Wenhui*
Consideration of cells as a problem for understanding the behavior of biomolecular processes and multicellular tissues in cells is a new field of research in the interface between physics and biology. Cellular materials exhibit a variety of physical and mechanical properties that can strongly influence both intracellular and multicellular biological events. This review summarizes how cells as substances link molecular biology to cellular and multicellular scale functions. In the field of cell biology and molecular biology, we review recent advances in the use of cellular material properties to guide cell fate decisions in the immune cell, neuron, stem cell, and cancer cell communities. Finally, we provide a perspective on how the properties of cellular materials can be integrated into the development of biophysical methods for artificial biological systems, regenerative medicine, and disease treatment
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