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Pancreatic neuroendocrine neoplasms: Review of clinically relevant information

Abstract

Jeannelyn Estrella

Pancreatic neuroendocrine neoplasms (PanNETs) are rare, representing approximately 3% of primary pancreatic neoplasms, although their incidence has risen sharply within the us, increasing quite 100% over the past three decades. within the past, classification of PanNETs has been fraught with different nomenclature and multiple grading and staging systems. The 2010 WHO Classification of Tumours of the gastrointestinal system and therefore the 7th edition of AJCC Cancer Staging Manual have tried to handle these issues, however, controversies still exist. This lecture will address this grading and staging systems, issues encountered in everyday practice, clinical significance and future direction.

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