皮肤病学和皮肤病杂志

A Case of Vitiligo Associated with Menieres Disease

Abstract

Min Jae Gwak, Eun Jae Shin, Min Kyung Shin, Ki-Heon Jung and Mu-Hyoung Lee

Vitiligo is a pigmentary skin disorder characterized by chronic and progressive loss of melanocytes. Although the etiology of vitiligo is still unknown, the most convincing theory is thought to an interaction between genetic and unknown environmental factors, resulting in autoimmune melanocyte destruction. Meniere's disease is characterized by recurrent vertigo, fluctuating or progressive sensorineural hearing loss and tinnitus, and it is associated with an accumulation of endolymph in the inner ear. Although its etiology is not known, genetic or epigenetic factors have a significant contribution. And recently many articles support the hypothesis that Meniere's disease is an autoimmune disorderand associated with immune-mediated disorder. Loss of otic melanocytes may occur in patients with vitiligo and, evidences of sensorineural hearing loss in vitiligo patients have been reported over the last decade. However, there have been no reports of Meniere's disease associated wth vitiligo patients. We report an interesting case of vitiligo on the face with Meniere's disease.