皮肤病学和皮肤病杂志

Halo Medium-Sized Congenital Melanocytic Nevi and Vitiligo Progression in Three Children

Abstract

Azael Freites-Martinez, Almudena Hernandez-Nuñez, Diego Martinez-Sanchez and Jesus Borbujo

Reports of halo nevus in medium-sized CMN are limited in the literature and its association with vitiligo is not very common. We present three healthy children with medium-sized CMN. There was no family history of vitiligo, other autoimmune disorders or melanoma. After years of follow up, the patients developed an achromic regular halo around the congenital nevus and one of them showed others halo nevi. Following these changes, achromic macules appeared and vitiligo was diagnosed. At follow-up, we observed reduction in size of the CMN and no thought-provoking malignant changes. Conclusion: We support that in halo medium sized CMN, like in other congenital nevi with unusual features, continuous observation should be recommended. Furthermore, parents should be informed about the long period of time required for complete resolution and the low possibility of malignant change in the nevus. Pediatricians should be familiar with this no life-threatening association.